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MOTS-C is a mitochondrial-derived research peptide studied in laboratory and preclinical models for its role in metabolic regulation, mitochondrial signaling, and cellular stress-response pathways. Supplied as a lyophilized powder for research use only.
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MOTS-C is a mitochondrial-derived peptide encoded within mitochondrial DNA and expressed across multiple tissues. In laboratory and preclinical research settings, MOTS-C has been studied for its role in cellular metabolism regulation, mitochondrial signaling, and adaptive stress responses.
Unlike nuclear-encoded peptides, MOTS-C is synthesized in the cytoplasm and has been observed to translocate to the nucleus under certain stress conditions in research models, where it may influence gene expression related to metabolic homeostasis. This product is supplied as a lyophilized powder intended strictly for laboratory research use.
⚠️ Research Use Only – Compliance Notice
- Cellular metabolism and energy regulation models
- Mitochondrial signaling and cross-talk with nuclear pathways
- Insulin sensitivity and glucose metabolism research
- AMPK activation and metabolic stress response pathways
- Skeletal muscle metabolism and exercise-related signaling models
- Aging-related metabolic regulation studies
- Cellular adaptation to oxidative and metabolic stress
Compound Name: MOTS-C
Peptide Classification: Mitochondrial-derived peptide
Amino Acid Length: 16
Amino Acid Sequence: MRWQEMGYIFYPRKLR
Molecular Formula: C101H152N28O22
Molecular Weight: ~2174.4 g/mol
CAS Number: 1628317-31-4
Form: Lyophilized powder
Solubility: Soluble in water under laboratory conditions
- Store at -20°C for long-term stability
- Refrigeration (2–8°C) acceptable for short-term storage
- Avoid repeated freeze-thaw cycles
- Protect from light and moisture
- Reconstituted material should be aliquoted to preserve integrity
- Handle using standard laboratory safety protocols




